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October 5, 2009

Long-Term Combination Antiretroviral Therapy Is Associated with the Risk of Coronary Plaques in African Americans with HIV Infection

"This study suggests that long-term exposure to ART may be associated with coronary plaques. Because long-term use of ART and HIV replication may be associated with the presence of noncalcified plaques, some of which may be more vulnerable to rupture, an intensive lifestyle intervention to reduce traditional risk factors for coronary artery disease (CAD) is ultimately vital to those who are on ART."

Read more in AIDS Patient Care and STDs, October 5, 2009.

Comment: This trial studied only African Americans. Therefore the same finding may apply to other patients as well -- which seems likely.