Reuters Health: "Researchers found that adding the supplement, called S-Adenosyl Methionine, or SAMe, to a patients' antidepressant treatment helped more people with major depression improve their symptoms than those that took an inactive placebo on top of their normal medication."
See the journal abstract at http://ajp.psychiatryonline.org/cgi/content/abstract/167/8/942
For an earlier review, see www.ajcn.org/cgi/reprint/76/5/1158S.pdf
Comment: Not an HIV-related study, but may be useful to some.
There could be drug-interaction and safety issues with SAMe -- which is often taken with certain B vitamins, and in lower doses than used in the recent study. Persons with serious health problems especially should get medical advice. But SAMe has not gone through the formal approval process, so some of the routine testing has not been done, and doctors don't have some of the answers.
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