"It is possible for resistance testing labs to tweak the standard tests so that they are better able to detect resistant virus in people with low virus levels. Data indicate this practice is occurring more frequently now than in the past. It is not a standardized practice, however, given a paucity of research indicating whether modified genotypic testing is sensitive enough to yield conclusive results.
"Hoping to answer this question, a team in London led by Nicola Mackie, MD, from the Imperial College Healthcare National Health Service Trust, examined the results of 7,861 HIV resistance tests—1,001 of which involved samples with viral loads below 1,000 copies—collected from 3,791 people."
Read more in POZ, March 30, 2010.
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