"This report documents the long-term sustainability of antiretroviral-therapy programs in resource-poor countries, with excellent rates of retention and adherence and a survival rate of 75% at 5 years. The WHO criteria of treatment failure are not sensitive or specific. Waiting to meet these criteria may delay the recognition of virologic failure and result in the accumulation of HIV-1 drug-resistance mutations."
Read more in New England Journal of Medicine, August 2-, 2009.
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