AIDS Treatment News logo      

January 17, 2011

Women Might Have More Favorable Blood Levels of Some HIV Drugs

POZ: "Mona Loutfy, MD, one of the study’s authors, reported that she and her colleagues found that the average minimum concentrations (Cmin) of at least two drugs—Viramune and Kaletra—were significantly higher than what has been found in previous studies in the general population, while minimum concentrations were lower than average in women taking Reyataz or Sustiva. The primary concern about blood levels is keeping them within a “therapeutic” range, whereby there is enough drug present to shut down HIV repliction almost entirely, but not so much that it increases the risk of side effects. The authors suggest, however, than maintaining a higher than average Cmin level, even within this therapeutic range, might confer a treatment advantage.

"Loutfy’s team also found, contrary to expectation, that the maximal concentrations (Cmax) of all four drugs was slightly lower than average in their study participants. A lower Cmax would, theoretically, predict fewer and less severe side effects in the women."

1 comments:

Gidon said...

RSS feed request to Before It's News
Hi,
I'm the health/Health Policy editor at Before It's News. Our site is a People Powered news platform with over 2,500,000 visits a month and growing fast.
We would be honored if we could republish AIDS Treatment News' RSS feed in our Health category. Our readers need to read what your blog has to say.
Syndicating to Before It's News is a terrific way spread the word and grow your audience. Many other organizations are using Before It's News to do just that. We can have your feed up and running in 24 hours. I just need you to reply with your permission to do so. Please include the full name and email of the person who will be attached to the account, and let me know the name you want on the account (most people have their name or their blog name).
You can also have any text and/or links you wish appended to the end or prepended to the beginning of each of your posts on Before It's News.
Just email me the text and links that you want at the beginning and/or ending of each post. If you know html you can send me that. If not, just send me the text and a link to your site. It should be around 200 characters or less (not including links).
You can, if you like, create a custom feed for Before It's News that includes multiple links back to your blog or web site. We only require that RSS feeds include full stories, not partial stories. We don't censor or edit work.
If you have any other blogs or websites you would like featured on before it's news, you can send the details for those feeds as well.
Thank you,
Gidon Belmaker
Editor, Before It's News
gidon@beforeitsnews.com
www.beforeitsnews.com