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March 4, 2010

Stopping Tenofovir Doesn’t Always Reverse Kidney Damage

"In conclusion, Wever’s group writes, 'improvements in renal function after tenofovir cessation is variable and incomplete, particularly in patients with more gradual decline in GFR who are not receiving a protease inhibitor.' They also suggest using a GFR below 90, as opposed to a CKD-defining GFR below 60, when determining whether to discontinue tenofovir treatment 'to avoid permanent renal dysfunction.'"

Read more in POZ, March 3, 2010.