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September 20, 2010

Longer viral load is undetectable, lower the risk of rebound

aidsmap: "'We found that once viral suppression was initially achieved, high levels of adherence were still needed for at least the first year. Over time, however, the risk of viral rebound decreased with maintained viral suppression irrespective of the level of adherence', comment the investigators.

"Nevertheless, the investigators emphasise that patients should aim to take all their doses correctly.

"Treatment with combination antiretroviral therapy can extend the life expectancy of HIV-positive patients to near normal levels.

"To get the maximum benefit from their treatment, it is necessary for patients to take their treatment correctly. The best outcomes are seen in individuals who take at least 95% of their doses. Adherence below that level has been associated with an increase in viral load and the development of drug-resistant virus."