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July 26, 2009

Kesho Bora study: Maternal ART during pregnancy and breastfeeding prevents more infections than short-course prophylaxis

"Antiretroviral treatment for mothers started during pregnancy and continued throughout the breastfeeding period resulted in a significantly lower rate of mother to child HIV transmission when compared with the standard short-course regimen, investigators on the Kesho Bora study reported this week at the Fifth International AIDS Society conference in Cape Town.

"The Kesho Bora study, conducted in Kenya, South Africa and Burkina Faso, found that antiretroviral treatment for the mother with a protease inhibitor-based regimen was significantly more effective than short course treatment in which the mother took AZT from week 28-36 of pregnancy with AZT/3TC and single dose nevirapine at the onset of labour, and AZT/3TC for one week, while the infant received single dose nevirapine with one weeek of AZT/3TC, and was either formula fed or breastfed with weaning at 6 months."

Read more in Aidsmap, July 24, 2009.