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December 27, 2009

Intermuscular tissue is decreased in HIV infection

"The first study in the main conference looked at a intermuscular adipose tissue (IMAT) - the distribution of fat that is beneath the muscle facia and muscle tissue – as a new parameter of metabolic disturbances. Led by Carl Grunfeld with the FRAM study, this group has provided important insight into the association of HIV to metabolic changes by using full body MRI to identify changes and including an HIV-negative control group. Results from the study concluded that fat loss and fat gain are separate unrelated dysfunctions and that fat loss rather than fat accumulation is the driving mechanism behind HIV-related changes."

Read more in HIV Treatment Bulletin, November/December, 2009.