AIDS Treatment News logo      

October 8, 2009

CD4 cell count below 500 increases cancer risk for patients with HIV

"Maintaining a CD4 cell count above 500 cells/mm3 will protect HIV-positive patients from a range of AIDS-defining and non-AIDS-defining cancers, French investigators conclude in a paper published online on October 8th inth Lancet Oncology.

"The investigators analysed the rates of the seven most common cancers in people with HIV and found that CD4 cell count was the strongest risk factor for several of them. Most of the patients in the study, which included data collected between 1998 and 2006, were taking antiretroviral therapy.

"'Our results suggest that combination antiretroviral therapy would be most beneficial if it restores or maintains the CD4 cell count above 500 cells/mm3, thereby indicating earlier diagnosis of HIV infection and earlier treatment initiation", comment the authors."

Read more in Aidsmap, October 8, 2009.