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October 11, 2010

B cells in early and chronic HIV infection: evidence for preservation of immune...

Blood: "At one year post-ART, the percentage of resting memory B cells remained higher in early compared to chronic HIV-infected individuals. This difference translated into a better functional profile in that memory B-cell responses to HIV and non-HIV antigens were superior in early- compared to chronic-treated HIV infected individuals. These findings provide new insights on B cells in HIV infection and how early initiation of ART may prevent irreversible immune system damage."