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July 8, 2010

Inflammation associated with increased mortality risk for patients with HIV, even when CD4 cell count high

Aidsmap: "High levels of two markers of inflammation – fibrinogen and C-reactive protein – are independently associated with an increased risk of mortality for patients with HIV, even when they have a strong immune system, US investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes.

“We found that elevated levels of fibrinogen and CRP [C-reactive protein] were strong and independent predictors of 5-year mortality risk. Our findings suggest an important role for inflammation in mortality risk”, comment the investigators."