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July 23, 2010

New International AIDS Society-USA Guidelines Recommend Starting Antiretroviral Therapy at 500 "Coinciding with the XVIII International AIDS Conference (AIDS 2010) this week in Vienna, the International AIDS Society-USA (IAS-USA) has released new antiretroviral therapy (ART) guidelines for adults with HIV. The updated guidelines, published in the July 21, 2010 Journal of the American Medical Association (JAMA) concur with the current U.S. Department of Health and Human Services recommendations, which advise that asymptomatic people should initiate ART when their CD4 T-cell count falls to 500 cells/mm3. But there is no CD4 count upper limit for starting treatment, and the expert panel recommended therapy for certain groups regardless of CD4 cell level. However, they emphasized, it is important to assess individual readiness before starting ART."

Comment: The two U.S. guidelines generally agree on important matters.